Hemagglutinin Antikörper (AA 465-566) (Alexa Fluor 350)

Produktnummer ABIN1692582

Produktdetails anti-Hemagglutinin Antikörper (Alexa Fluor 350)

Target: Hemagglutinin (HA)

Bindungsspezifität: AA 465-566

Reaktivität: Virus, Influenza A Virus H3N1

Virus Strain: A/environment/North Dakota/NWRC185233-06/2007

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hemagglutinin Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Virus

Kreuzreaktivität (Details): Influenza A virus H3N1

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from hemagglutinin [Influenza A virus A/environment/North Dakota/NWRC185233-06/2007(H3N1)]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Hemagglutinin

Target: Hemagglutinin (HA)

Andere Bezeichnung: Hemagglutinin (HA Produkte)

Synonyme: hemagglutinin antikoerper, Hemagglutinin antikoerper, HA antikoerper, HA antikoerper, ha antikoerper

Substanzklasse: Influenza Protein

Hintergrund:

Synonyms: HA, Influenza A virus H3N1, hemagglutinin, H3N1, H3N1 hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, K9URT3_9INFA.

Background: Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80 % of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.