GABRA4 Antikörper (AA 36-258)

Produktnummer ABIN1679929

Produktdetails anti-GABRA4 Antikörper

Target: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Bindungsspezifität: AA 36-258

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QNQKEEKLCT ENFTRILDSL LDGYDNRLRP GFGGPVTEVK TDIYVTSFGP VSDVEMEYTM DVFFRQTWID KRLKYDGPIE ILRLNNMMVT KVWTPDTFFR NGKKSVSHNM TAPNKLFRIM RNGTILYTMR LTISAECPMR LVDFPMDGHA CPLKFGSYAY PKSEMIYTWT KGPEKSVEVP KESSSLVQYD LIGQTVSSET IKSITGEYIV MTVYFHLRRK MGY

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-258 of human GABRA4 (NP_000800.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GABRA4

Target: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Andere Bezeichnung: GABRA4 (GABRA4 Produkte)

Synonyme: GABRA4 antikoerper, Gabra-4 antikoerper, gamma-aminobutyric acid type A receptor alpha4 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 antikoerper, GABRA4 antikoerper, Gabra4 antikoerper

Hintergrund: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.,GABRA4,Neuroscience,GABRA4

Molekulargewicht: 61 kDa

Gen-ID: 2557

UniProt: P48169

Pathways: Synaptic Membrane