RYBP Antikörper
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- Target Alle RYBP Antikörper anzeigen
- RYBP (RING1 and YY1 Binding Protein (RYBP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RYBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects DEDAF. A 32 kDa band should be detected.
- Aufreinigung
- Affinity purified
- Immunogen
- Synthetic peptide surrounding amino acid 218 of human DEDAF.
- Top Product
- Discover our top product RYBP Primärantikörper
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- Applikationshinweise
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Western Blot: 0.5-4 μg/mL. A549 or HepG2 cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C/-80 °C
- Informationen zur Lagerung
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Target
- RYBP (RING1 and YY1 Binding Protein (RYBP))
- Andere Bezeichnung
- RYBP (RYBP Produkte)
- Synonyme
- AAP1 antikoerper, DEDAF antikoerper, YEAF1 antikoerper, 2410018J24Rik antikoerper, rybp antikoerper, aap1 antikoerper, dedaf antikoerper, yeaf1 antikoerper, cb337 antikoerper, wu:fi34f03 antikoerper, Dedaf antikoerper, zgc:153842 antikoerper, RING1 and YY1 binding protein antikoerper, RING1 and YY1 binding protein L homeolog antikoerper, RING1 and YY1 binding protein a antikoerper, RING1 and YY1 binding protein b antikoerper, RYBP antikoerper, Rybp antikoerper, rybp antikoerper, rybp.L antikoerper, rybpa antikoerper, rybpb antikoerper
- Hintergrund
- Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.Synonyms: AAP-1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Death effector domain-associated factor, RING1 and YY1-binding protein, YEAF1, YY1 and E4TF1-associated factor 1
- Gen-ID
- 23429
- NCBI Accession
- NP_036366
- UniProt
- Q8N488
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