This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This COL4A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-859 amino acids from the Central region of human COL4A6.
CXDELq22.3 antikoerper, DELXq22.3 antikoerper, BB116301 antikoerper, collagen type IV alpha 6 chain antikoerper, collagen, type IV, alpha 6 antikoerper, COL4A6 antikoerper, Col4a6 antikoerper, col4a6 antikoerper
Hintergrund
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.