GRIK5 Antikörper (AA 969-980)

Produktnummer ABIN1492538

Produktdetails anti-GRIK5 Antikörper

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Bindungsspezifität: AA 969-980

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GRIK5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human GRIK5.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Dog (100%) Bovine (92%) Mouse, Rat (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-GPAGPRELAEHE from the C-terminus of human GRIK5 (NP_002079.3). Percent identity by BLAST analysis: Human, Chimpanzee, Dog (100%), Bovine (92%), Mouse, Rat (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx. 26  kDa band in Human Brain (Frontal Cortex and Hippocampus) lysates after 1 μg/mL antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 109  kDa according to NP_002079.3. The 26  kDa band was successfully blocked by incubation with the immunizing peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu GRIK5

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Andere Bezeichnung: GRIK5 / KA2 (GRIK5 Produkte)

Synonyme: EAA2 antikoerper, GRIK2 antikoerper, GluK5 antikoerper, KA2 antikoerper, GRIK5 antikoerper, Glur6 antikoerper, ka2 antikoerper, eaa2 antikoerper, GluRgamma2 antikoerper, iGlu5 antikoerper, glutamate ionotropic receptor kainate type subunit 5 antikoerper, glutamate receptor, ionotropic, kainate 5 antikoerper, glutamate ionotropic receptor kainate type subunit 2 antikoerper, glutamate receptor, ionotropic, kainate 5 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 5 (gamma 2) antikoerper, GRIK5 antikoerper, GRIK2 antikoerper, grik5 antikoerper, grik5.L antikoerper, Grik5 antikoerper

Hintergrund: Name/Gene ID: GRIK5
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIK5, EAA2, Glutamate receptor KA2, KA2, GluK5, Glutamate receptor KA-2

Gen-ID: 2901

NCBI Accession: NP_002079

UniProt: Q16478

Pathways: Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis