Dopamine d2 Receptor Antikörper

Produktnummer ABIN1450212

Produktdetails anti-Dopamine d2 Receptor Antikörper

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Human Dopamine Receptor D2 (family: GPCR, subfamily: Dopamine). BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except ZNF57 (42 %).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: Dopamine D2 Receptor (DRD2 Produkte)

Synonyme: D2DR antikoerper, D2R antikoerper, drd2b antikoerper, d2r2 antikoerper, Drd-2 antikoerper, d2dr antikoerper, d2r antikoerper, drd2 antikoerper, drd2-B antikoerper, DRD2 antikoerper, D2 antikoerper, CG18741 antikoerper, CG7569 antikoerper, DAMB antikoerper, DDR2 antikoerper, DOPR2 antikoerper, DOPR99B antikoerper, Dar2 antikoerper, Dmel\\CG18741 antikoerper, DopD1 antikoerper, DopR99B antikoerper, DopRII antikoerper, dopamine receptor D2 antikoerper, dopamine receptor D2 like antikoerper, dopamine receptor D2 L homeolog antikoerper, dopamine receptor D2 S homeolog antikoerper, Dopamine 1-like receptor 2 antikoerper, DRD2 antikoerper, drd2l antikoerper, drd2 antikoerper, Drd2 antikoerper, drd2.L antikoerper, drd2.S antikoerper, Dop1R2 antikoerper

Hintergrund: The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.Synonyms: D(2) dopamine receptor, DRD2

Gen-ID: 1813

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity