TMEM237 Antikörper (Middle Region)

Produktnummer ABIN1449912

Produktdetails anti-TMEM237 Antikörper

Target: TMEM237 (Transmembrane Protein 237 (TMEM237))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM237 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGDQLSNLSN LLQQYKTLAY PFQSLLYLLL ALSTISAFDR IDFAKISVAI

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human ALS2CR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu TMEM237

Target: TMEM237 (Transmembrane Protein 237 (TMEM237))

Andere Bezeichnung: ALS2CR4 / TMEM237 (TMEM237 Produkte)

Synonyme: ALS2CR4 antikoerper, JBTS14 antikoerper, Als2cr4 antikoerper, AI853305 antikoerper, Gm972 antikoerper, als2cr4 antikoerper, als2cr4a antikoerper, si:dkey-33m14.6 antikoerper, als2cr4b antikoerper, sb:cb992 antikoerper, zgc:101660 antikoerper, transmembrane protein 237 antikoerper, transmembrane protein 237a antikoerper, transmembrane protein 237 L homeolog antikoerper, transmembrane protein 237b antikoerper, TMEM237 antikoerper, Tmem237 antikoerper, tmem237 antikoerper, tmem237a antikoerper, tmem237.L antikoerper, tmem237b antikoerper

Hintergrund: TMEM237 or ALS2CR4 is a component of the transition zone in primary cilia and required for ciliogenesis. Defects in TMEM237 are the cause of Joubert syndrome type 14 (JBTS14). An autosomal recessive disorder characterized by severe mental retardation, hypotonia, breathing abnormalities in infancy, and dysmorphic facial features. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable JBTS14 features include renal disease, abnormal eye movements, and postaxial polydactyly.Synonyms: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein, Transmembrane protein 237

Gen-ID: 65062

NCBI Accession: NM_001044385