ARNTL2 Antikörper (C-Term, Middle Region)

Produktnummer ABIN1449887

Produktdetails anti-ARNTL2 Antikörper

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Bindungsspezifität: C-Term, Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARNTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AILGYLPQEL LGTSCYEYFH QDDHSSLTDK HKAVLQSKEK ILTDSYKFRV

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Human, Bovine, DogSpecies reactivity (tested):Mouse

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle regionl of mouse ARNTL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu ARNTL2

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Andere Bezeichnung: ARNTL2 / BMAL2 (ARNTL2 Produkte)

Synonyme: BMAL2 antikoerper, CLIF antikoerper, MOP9 antikoerper, PASD9 antikoerper, bHLHe6 antikoerper, bmal2 antikoerper, wu:fj90c09 antikoerper, 4632430A05Rik antikoerper, Arnt4 antikoerper, Bmal2 antikoerper, ARNTL2 antikoerper, aryl hydrocarbon receptor nuclear translocator like 2 antikoerper, aryl hydrocarbon receptor nuclear translocator-like 2 antikoerper, ARNTL2 antikoerper, arntl2 antikoerper, Arntl2 antikoerper

Hintergrund: ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. It is xxpressed in fetal brain and highly expressed in brain and placenta. Lower levels are found in heart, liver, thymus, kidney and lung. It is located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN) and also detected in endothelial cells of the heart, lung and kidney. In the brain, it is specifically expressed in the thalamus, hippocampus and amygdala.Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 2, BHLHE6, Basic-helix-loop-helix-PAS protein MOP9, Brain and muscle ARNT-like 2, CLIF, CYCLE-like factor, Class E basic helix-loop-helix protein 6, MOP9, Member of PAS protein 9, PAS domain-containing protein 9, PASD9, bHLHe6

Gen-ID: 272322

NCBI Accession: NP_758513

Pathways: Photoperiodism