SYT2 Antikörper (N-Term)

Produktnummer ABIN1449191

Produktdetails anti-SYT2 Antikörper

Target: SYT2 (Synaptotagmin II (SYT2))

Bindungsspezifität: AA 1-20, N-Term

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SYT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Sequenz: MRNIFKRNQE PIVAPATTTA

Spezifität: This antibody reacts with Synaptotagmin 2.

Kreuzreaktivität (Details): Species reactivity (tested):Rat

Immunogen: Synthesized peptide which corresponding to rat synaptotagmin 2 N-terminus (1-20 aa)

Klon: 8G2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu SYT2

Target: SYT2 (Synaptotagmin II (SYT2))

Andere Bezeichnung: Synaptotagmin-2 (SYT2 Produkte)

Synonyme: SytII antikoerper, RATSYNII antikoerper, SYNII antikoerper, R74640 antikoerper, mKIAA4194 antikoerper, si:ch211-236j4.1 antikoerper, synaptotagmin 2 antikoerper, synaptotagmin II antikoerper, synaptotagmin IIa antikoerper, SYT2 antikoerper, Syt2 antikoerper, syt2a antikoerper, syt2 antikoerper

Hintergrund: Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, ß-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SYT-2, SYT2, SYTII, Synaptotagmin 2, Synaptotagmin II

Molekulargewicht: 60 kDa

Gen-ID: 127833

NCBI Accession: NP_001129976

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis