P2RY11 Antikörper (AA 71-170) (HRP)

Produktnummer ABIN1412882

Der Kaninchen Polyklonal anti-P2RY11 Antikörper wird verwendet zum Nachweis von P2RY11 in Proben von Human. Er wurde validiert für ELISA, IHC (p) und IHC (fro).

Kurzübersicht für P2RY11 Antikörper (AA 71-170) (HRP) (ABIN1412882)

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RY11 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-P2RY11 Antikörper (HRP)

Bindungsspezifität: AA 71-170

Kreuzreaktivität: Human

Homologie: Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu P2RY11

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Andere Bezeichnung: P2Y11

Hintergrund:

Synonyms: P2RY11, P2Y purinoceptor 11, P2Y11, P2Y11 receptor, P2Y11_HUMAN, Purinergic receptor P2Y G protein coupled 11, Purinergic receptor P2Y11.

Background: P2Y purinoceptor 11 (P2Y11) is a 374 amino acid protein belonging to the G-protein coupled receptor one family. P2Y11 is a multi-pass cell membrane protein that acts as a receptor for both ATP and ATD coupled to G proteins. Due to these interactions, P2Y11 is involved in phosphatidylinositol-calcium and adenylyl cyclase pathways. Induced by DMSO and retinoic acid, P2Y11 is highly expressed in spleen tissue. A putative trans-splicing event involving the gene that encodes P2Y11 and an upstream gene encoding PPAN has been found to result in a fusion protein, designated PPAN-P2RY11.

Gen-ID: 5032

UniProt: Q96G91

Pathways: cAMP Metabolic Process