COL25A1 Antikörper (AA 581-654) (Cy3)

Produktnummer ABIN1410375

Produktdetails anti-COL25A1 Antikörper (Cy3)

Target: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Bindungsspezifität: AA 581-654

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL25A1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLACP/COL25A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu COL25A1

Target: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Andere Bezeichnung: CLACP/COL25A1 (COL25A1 Produkte)

Synonyme: COL25A1 antikoerper, AMY antikoerper, CLAC antikoerper, CLAC-P antikoerper, CLACP antikoerper, 2700062B08Rik antikoerper, collagen type XXV alpha 1 chain antikoerper, collagen, type XXV, alpha 1 antikoerper, COL25A1 antikoerper, col25a1 antikoerper, Col25a1 antikoerper

Hintergrund:

Synonyms: Alzheimer disease amyloid associated protein, AMY, CLAC, CLAC P, CLAC precursor, COL25A1, COL25A1 protein, Collagen alpha 1 XXV chain, Collagen alpha 1XXV chain, Collagen like Alzheimer amyloid plaque component, Collagen like Alzheimer amyloid plaque component precursor, Collagen type XXV alpha 1, Collagenous Alzheimer amyloid plaque component.

Background: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.