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Netrin 3 Antikörper (AA 401-500) (Cy5.5)

Ntn3 Reaktivität: Human, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN1406915
  • Target Alle Netrin 3 (Ntn3) Antikörper anzeigen
    Netrin 3 (Ntn3)
    Bindungsspezifität
    • 14
    • 9
    • 9
    • 7
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 32
    • 15
    • 1
    Human, Ratte
    Wirt
    • 32
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Netrin 3 Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 32
    • 15
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NTN3/Netrin-3
    Isotyp
    IgG
    Top Product
    Discover our top product Ntn3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Netrin 3 (Ntn3)
    Andere Bezeichnung
    NTN3/Netrin-3 (Ntn3 Produkte)
    Synonyme
    NTN1 antikoerper, NTN2L antikoerper, Ntn2l antikoerper, netrin 3 antikoerper, netrin 1 antikoerper, NTN3 antikoerper, Ntn3 antikoerper
    Hintergrund

    Synonyms: NET3_HUMAN, Netrin-2-like protein, Netrin-3, NTN2L, NTN3.

    Background: Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, rather than attracted, by the netrin gradient. Neogenin serves as the primary guidance receptor for netrin-3. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection. Neogenin serves as the primary guidance receptor for netrin-3. During peripheral nerve development, high netrin-3 expression has been detected in mesenchymal cells, sensory ganglia and muscles. In humans, the gene encoding for the netrin-3 protein is localized to chromosome 16p13.3.

    Pathways
    Regulation of Muscle Cell Differentiation
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