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Kcng2 Antikörper (Alexa Fluor 647)

Kcng2 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1405068
  • Target Alle Kcng2 Antikörper anzeigen
    Kcng2 (Potassium Voltage-Gated Channel, Subfamily G, Member 2 (Kcng2))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kcng2 Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 26
    • 12
    • 11
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KCNG2
    Isotyp
    IgG
    Top Product
    Discover our top product Kcng2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Kcng2 (Potassium Voltage-Gated Channel, Subfamily G, Member 2 (Kcng2))
    Andere Bezeichnung
    KCNG2 (Kcng2 Produkte)
    Synonyme
    KCNF2 antikoerper, KV6.2 antikoerper, AA591524 antikoerper, Kv6.2 antikoerper, CKV6.2 antikoerper, KCNG4 antikoerper, potassium voltage-gated channel modifier subfamily G member 2 antikoerper, potassium voltage-gated channel, subfamily G, member 2 antikoerper, KCNG2 antikoerper, Kcng2 antikoerper
    Hintergrund

    Synonyms: Cardiac potassium channel subunit, KCNG2, KCNG2_HUMAN, KV6.2, Potassium voltage-gated channel subfamily G member 2, Voltage-gated potassium channel subunit Kv6.2.

    Background: Neuronal and cardiac cells are excited by voltage-gated ion channels. Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. Mutations interfering with potassium ion channels are known to cause a variety of disorders. KCNG2 (potassium voltage-gated channel subfamily G member 2) is also known as voltage-gated potassium channel subunit KV6.2, cardiac potassium channel subunit or KCNF2 and is a 466 amino acid protein. KCNG2 is a multi-pass membrane protein abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and detected at lower concentrations in brain, lung and placenta. KCNG2 is an electrically silent subunit that forms heterodimers with KV2.1, creating a unique functional K+ channel. KCNG2-KV2.1 heterodimers are known to be inhibited by tetraethylammonium and propafenone. KCNG2 is thought to downregulate potassium channel currents because KCNG2-KV2.1 heterodimers generate smaller currents than KV2.1 homodimers

    Gen-ID
    26251
    UniProt
    Q9UJ96
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