PGGT1B Antikörper (Alexa Fluor 350)

Produktnummer ABIN1403355

Produktdetails anti-PGGT1B Antikörper (Alexa Fluor 350)

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGGT1B Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGGT1B/FNTB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PGGT1B

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Andere Bezeichnung: PGGT1B (PGGT1B Produkte)

Synonyme: MGC115505 antikoerper, BGGI antikoerper, GGTI antikoerper, 2010207C17Rik antikoerper, 2610100E13 antikoerper, AI451237 antikoerper, AI551093 antikoerper, BGG1 antikoerper, GGT1 antikoerper, protein geranylgeranyltransferase type I subunit beta antikoerper, protein geranylgeranyltransferase type I, beta subunit S homeolog antikoerper, protein geranylgeranyltransferase type 1 subunit beta antikoerper, protein geranylgeranyltransferase type I, beta subunit antikoerper, PGGT1B antikoerper, pggt1b.S antikoerper, Pggt1b antikoerper

Hintergrund:

Synonyms: CAAX farnesyltransferase subunit beta, EC 2.5.1.58, EC=2.5.1.58, Farnesyltransferase, farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FNTB, FNTB_HUMAN, FPTB, FTase beta, FTase-beta, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, Ras proteins prenyltransferase subunit beta.

Background: Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

Gen-ID: 2342