ANKRD6 Antikörper (Alexa Fluor 488)

Produktnummer ABIN1400242

Produktdetails anti-ANKRD6 Antikörper (Alexa Fluor 488)

Target: ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD6 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD6/Diversin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANKRD6

Target: ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))

Andere Bezeichnung: ANKRD6 (ANKRD6 Produkte)

Synonyme: ANKRD6 antikoerper, ankrd6 antikoerper, diversin antikoerper, si:dkey-181i3none antikoerper, ankyrin repeat domain 6 antikoerper, ankyrin repeat domain 6b antikoerper, ANKRD6 antikoerper, ankrd6b antikoerper, Ankrd6 antikoerper

Hintergrund:

Synonyms: ANKRD 6, ankyrin repeat domain 6, ANKR6_HUMAN, Ankyrin repeat domain-containing protein 6, Diversin.

Background: Diversin, also known as ANKRD6 (ankyrin repeat domain 6), is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner and at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl (dishevelled), an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase I?. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.