LGR6 Antikörper (AA 401-500) (Alexa Fluor 350)

Produktnummer ABIN1400001

Produktdetails anti-LGR6 Antikörper (Alexa Fluor 350)

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Bindungsspezifität: AA 401-500

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGR6 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LGR6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LGR6

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Andere Bezeichnung: LGR6 (LGR6 Produkte)

Synonyme: LGR6 antikoerper, GPCR antikoerper, VTS20631 antikoerper, A530037C04Rik antikoerper, D830026M09 antikoerper, RGD1560339 antikoerper, leucine rich repeat containing G protein-coupled receptor 6 antikoerper, leucine-rich repeat-containing G protein-coupled receptor 6 antikoerper, LGR6 antikoerper, Lgr6 antikoerper

Hintergrund:

Synonyms: GPCR, VTS20631, Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6, UNQ6427/PRO213

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Gen-ID: 59352

UniProt: Q9HBX8