FNDC3B Antikörper (AA 921-1020) (Alexa Fluor 488)

Produktnummer ABIN1399324

Produktdetails anti-FNDC3B Antikörper (Alexa Fluor 488)

Target: FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))

Bindungsspezifität: AA 921-1020

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNDC3B Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNDC3B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FNDC3B

Target: FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))

Andere Bezeichnung: FNDC3B (FNDC3B Produkte)

Synonyme: FAD104 antikoerper, PRO4979 antikoerper, YVTM2421 antikoerper, 1600019O04Rik antikoerper, AW550168 antikoerper, Fad104 antikoerper, mKIAA4164 antikoerper, RGD1311673 antikoerper, FNDC3B antikoerper, DKFZp469D136 antikoerper, fibronectin type III domain containing 3B antikoerper, FNDC3B antikoerper, Fndc3b antikoerper, fndc3b antikoerper

Hintergrund:

Synonyms: Factor for adipocyte dferentiation 104, FAD104, fibronectin type III domain containing 3B, FLJ23399, HCV NS5A binding protein 37, NS5ABP37, YVTM2421, MGC10002, PRO4979, DKFZp686D14170, DKFZp762K137, FND3B_HUMAN.

Background: Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.

Gen-ID: 64778

Pathways: Positive Regulation of fat Cell Differentiation