FBXL5 Antikörper (AA 31-130) (Alexa Fluor 350)

Produktnummer ABIN1399263

Produktdetails anti-FBXL5 Antikörper (Alexa Fluor 350)

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Bindungsspezifität: AA 31-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL5 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXL5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FBXL5

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Andere Bezeichnung: FBXL5 (FBXL5 Produkte)

Synonyme: fbxl5 antikoerper, MGC53238 antikoerper, FBXL5 antikoerper, FBL4 antikoerper, FBL5 antikoerper, FLR1 antikoerper, Fbl4 antikoerper, Fir4 antikoerper, wu:fb52d06 antikoerper, F-box and leucine rich repeat protein 5 antikoerper, F-box and leucine-rich repeat protein 5 S homeolog antikoerper, F-box and leucine-rich repeat protein 5 L homeolog antikoerper, F-box and leucine-rich repeat protein 5 antikoerper, FBXL5 antikoerper, fbxl5.S antikoerper, fbxl5.L antikoerper, fbxl5 antikoerper, Fbxl5 antikoerper

Hintergrund:

Synonyms: F box and leucine rich repeat protein 5, F box/LRR repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, F-box/LRR-repeat protein 5, FBL4, FBL5, FBXL5, FBXL5_HUMAN, FLR1, p45SKP2 like protein, p45SKP2-like protein.

Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Gen-ID: 26234

Pathways: Transition Metal Ion Homeostasis