Lin28A/ B (AA 75-180) Antikörper (Alexa Fluor 488)
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- Target
- Lin28A/ B
- Bindungsspezifität
- AA 75-180
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Alexa Fluor 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- This antibody is produced using synthetic peptide that falls within the range of 90-120 amino acids of human Lin28A. Due to 92 % sequence similarity, this antibody may cross react with Lin28B.
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Lin28A
- Isotyp
- IgG
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anti-Lin28A/ B (AA 75-180) antibody
Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- Lin28A/ B
- Andere Bezeichnung
- Lin28A/B
- Hintergrund
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Synonyms: Protein lin-28 homolog A, LIN28A, Lin-28A, Zinc finger CCHC domain-containing protein 1, CSDD1, LIN28, ZCCHC1, Protein lin-28 homolog B, LIN28B, Lin-28B, CSDD2
Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.
- Gen-ID
- 79727, 389421
- UniProt
- Q6ZN17
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