BEND4 Antikörper (AA 351-450) (Alexa Fluor 488)

Produktnummer ABIN1399090

Produktdetails anti-BEND4 Antikörper (Alexa Fluor 488)

Target: BEND4 (BEN Domain Containing 4 (BEND4))

Bindungsspezifität: AA 351-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BEND4 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BEND4/CCDC4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BEND4

Target: BEND4 (BEN Domain Containing 4 (BEND4))

Andere Bezeichnung: BEND4 (BEND4 Produkte)

Synonyme: CCDC4 antikoerper, D330027G24Rik antikoerper, EG666938 antikoerper, BEN domain containing 4 antikoerper, BEND4 antikoerper, Bend4 antikoerper

Hintergrund:

Synonyms: BEN domain containing 4, BEN domain containing protein 4, BEN domain-containing protein 4, Bend4, BEND4_HUMAN, CCDC4, Coiled coil domain containing 4, Coiled coil domain containing protein 4, Coiled-coil domain-containing protein 4, FLJ35632, FLJ43965, MGC157807, MGC157808.

Background: BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates proteinDNA and proteinprotein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.