UBE2M Antikörper (AA 1-100) (Alexa Fluor 555)

Produktnummer ABIN1398761

Produktdetails anti-UBE2M Antikörper (Alexa Fluor 555)

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Bindungsspezifität: AA 1-100

Reaktivität: Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2M Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Xenopus laevis

Homologie: Human,Mouse,Rat,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2M

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2M

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Andere Bezeichnung: UBE2M (ube2m Produkte)

Synonyme: DDBDRAFT_0204633 antikoerper, DDBDRAFT_0238042 antikoerper, DDB_0204633 antikoerper, DDB_0238042 antikoerper, UBC-RS2 antikoerper, UBC12 antikoerper, hUbc12 antikoerper, 2510040H03Rik antikoerper, Ubc-rs2 antikoerper, ubiquitin conjugating enzyme E2M antikoerper, ubiquitin-conjugating enzyme E2M antikoerper, ubiquitin conjugating enzyme E2 M antikoerper, NEDD8-conjugating enzyme antikoerper, ubiquitin conjugating enzyme E2M S homeolog antikoerper, ube2m antikoerper, LOC692934 antikoerper, UBE2M antikoerper, Ube2m antikoerper, ube2m.S antikoerper

Hintergrund:

Synonyms: hUbc12, NEDD8 carrier protein, NEDD8 conjugating enzyme Ubc12, NEDD8 protein ligase, NEDD8-conjugating enzyme Ubc12, UBC-RS2, UBC12, UBC12_HUMAN, ube2m, ubiquitin carrier protein M, Ubiquitin conjugating enzyme E2 M, Ubiquitin-conjugating enzyme E2 M, ubiquitin-protein ligase M, yeast UBC12 homolog.

Background: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.

Gen-ID: 9040