ESR2 Antikörper (pSer87) (Alexa Fluor 350)

Produktnummer ABIN1397682

Produktdetails anti-ESR2 Antikörper (Alexa Fluor 350)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Bindungsspezifität: pSer87

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESR2 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Estrogen Receptor beta around the phosphorylation site of Ser87 [HL(p-S)PL]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Andere Bezeichnung: Estrogen Receptor beta (ESR2 Produkte)

Synonyme: ER-BETA antikoerper, ESR-BETA antikoerper, ESRB antikoerper, ESTRB antikoerper, Erb antikoerper, NR3A2 antikoerper, ER[b]1 antikoerper, zfER-beta1 antikoerper, zfER[b]1 antikoerper, erb2 antikoerper, CERB antikoerper, ERB antikoerper, erb antikoerper, esrb antikoerper, estrb antikoerper, nr3a2 antikoerper, ERbeta antikoerper, er-beta antikoerper, esr-beta antikoerper, ESR2 antikoerper, ERBETA antikoerper, er antikoerper, ER-beta antikoerper, ER[b] antikoerper, Estrb antikoerper, ER[b]2 antikoerper, ER[b]a antikoerper, zfER[b]2 antikoerper, zfER-beta2 antikoerper, Erb2 antikoerper, esr2 antikoerper, erbeta antikoerper, Esr2 antikoerper, ERBeta2 antikoerper, estrogen receptor 2 antikoerper, estrogen receptor 2b antikoerper, estrogen receptor beta 2 antikoerper, estrogen receptor 2 (beta) antikoerper, estrogen receptor 2a antikoerper, estrogen receptor beta antikoerper, ESR2 antikoerper, esr2b antikoerper, erb2 antikoerper, esr2 antikoerper, Esr2 antikoerper, esr2a antikoerper, erbeta antikoerper

Hintergrund:

Synonyms: Estrogen Receptor beta phospho S87, Estrogen Receptor beta phospho Ser87, p-ER betaS87, p-ER betaSer87, ER-betaSer87, ER-betaS87, Estrogen receptor-beta, ER BETA, ER-BETA, ER-beta, Erb, ESR 2, ESR 2, ESR B, ESR-B, ESR BETA, ESR-BETA, ESR2, ESR2, ESR2_HUMAN, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 ER beta, Estrogen Receptor 2, Estrogen Receptor-2, estrogen receptor beta 4, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2.

Background: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER alpha and ER beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ER alpha and ER beta A have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and ER beta may be regulated by distinct mechanisms even though they share many functional characteristics.

Gen-ID: 2100

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling