KCNF1 Antikörper (AA 161-260) (Biotin)

Produktnummer ABIN1395583

Produktdetails anti-KCNF1 Antikörper (Biotin)

Target: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Bindungsspezifität: AA 161-260

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNF1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu KCNF1

Target: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Andere Bezeichnung: KCNF1 (KCNF1 Produkte)

Synonyme: kcnf1 antikoerper, si:dkey-65b13.5 antikoerper, KCNF1 antikoerper, ik8 antikoerper, kh1 antikoerper, kcnf antikoerper, kv5.1 antikoerper, IK8 antikoerper, KCNF antikoerper, KV5.1 antikoerper, kH1 antikoerper, Gm1182 antikoerper, Kv5.1 antikoerper, Kh1 antikoerper, potassium voltage-gated channel, subfamily F, member 1a antikoerper, potassium voltage-gated channel modifier subfamily F member 1 antikoerper, potassium channel, voltage gated modifier subfamily F, member 1 antikoerper, potassium voltage-gated channel, subfamily F, member 1 antikoerper, kcnf1a antikoerper, KCNF1 antikoerper, kcnf1 antikoerper, Kcnf1 antikoerper

Hintergrund:

Synonyms: IK 8, IK8, KCNF 1, KCNF, Kcnf1, KCNF1_HUMAN, kH 1, kH1, KV5.1, Potassium voltage-gated channel subfamily F member 1, MGC33316, Potassium channel KH1, Potassium channel Kv5.1, Potassium voltage gated channel subfamily F member 1, Potassium voltage-gated channel subfamily F member 1, Voltage gated potassium channel subunit Kv5.1, Voltage-gated potassium channel subunit Kv5.1.

Background: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.