LRFN1 Antikörper (AA 181-290) (AbBy Fluor® 350)
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- Target Alle LRFN1 Antikörper anzeigen
- LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))
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Bindungsspezifität
- AA 181-290
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LRFN1 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LRFN1
- Isotyp
- IgG
- Top Product
- Discover our top product LRFN1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))
- Andere Bezeichnung
- LRFN1 (LRFN1 Produkte)
- Synonyme
- SALM2 antikoerper, BC004018 antikoerper, Semo1 antikoerper, leucine rich repeat and fibronectin type III domain containing 1 antikoerper, LRFN1 antikoerper, Lrfn1 antikoerper
- Hintergrund
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Synonyms: Leucine rich repeat and fibronectin type III domain containing 1, Leucine rich repeat and fibronectin type III domain containing protein 1, Leucine-rich repeat and fibronectin type III domain-containing protein 1, LRFN 1, lrfn1, LRFN1_HUMAN, SALM 2, SALM2, Synaptic adhesion like molecule 2, Synaptic adhesion-like molecule 2.
Background: LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
- Pathways
- Synaptic Membrane
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