SCN2B Antikörper (AA 65-180) (Alexa Fluor 647)

Produktnummer ABIN1395288

Produktdetails anti-SCN2B Antikörper (Alexa Fluor 647)

Target: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Bindungsspezifität: AA 65-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN2B Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCN2B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SCN2B

Target: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Andere Bezeichnung: SCN2B (SCN2B Produkte)

Synonyme: SCNB2 antikoerper, 2810451E09Rik antikoerper, AI840361 antikoerper, Gm183 antikoerper, SCN2B antikoerper, sodium voltage-gated channel beta subunit 2 antikoerper, sodium channel, voltage-gated, type II, beta antikoerper, sodium voltage-gated channel beta subunit 2 L homeolog antikoerper, SCN2B antikoerper, Scn2b antikoerper, scn2b.L antikoerper, scn2b antikoerper

Hintergrund:

Synonyms: Neuronal voltage gated sodium channel beta 2 subunit, Scn 2b, Scn2b, SCN2B_HUMAN, Sodium channel beta 2 subunit, Sodium channel subunit beta 2, Sodium channel subunit beta-2, Sodium channel voltage gated type II beta, Sodium channel voltage gated type II beta polypeptide.

Background: Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.