GABRG3 Antikörper (Alexa Fluor 555)

Produktnummer ABIN1395041

Produktdetails anti-GABRG3 Antikörper (Alexa Fluor 555)

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRG3 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABRG3

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Andere Bezeichnung: Gabrg3/Gaba A Receptor gamma 3 (GABRG3 Produkte)

Synonyme: GABRG3 antikoerper, B230362M20Rik antikoerper, Gabrg-3 antikoerper, gamma-aminobutyric acid type A receptor gamma3 subunit antikoerper, gamma-aminobutyric acid receptor subunit gamma-3 antikoerper, gamma-aminobutyric acid type A receptor gamma 3 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 antikoerper, GABRG3 antikoerper, gabrg3 antikoerper, LOC100011485 antikoerper, Gabrg3 antikoerper

Hintergrund:

Synonyms: GABAA receptor, GABAA receptor subunit gamma 3, GABR G3, GABRG 3, GABRG3, Gamma aminobutyric acid GABA A receptor gamma 3, Gamma aminobutyric acid A receptor gamma 3, Gamma aminobutyric acid receptor subunit gamma 3, GBRG3_HUMAN.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.