GRIK3 Antikörper (AA 501-600) (Alexa Fluor 647)

Produktnummer ABIN1394616

Produktdetails anti-GRIK3 Antikörper (Alexa Fluor 647)

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Bindungsspezifität: AA 501-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK3 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRIK3/GLR7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GRIK3

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Andere Bezeichnung: GRIK3/GLR7 (GRIK3 Produkte)

Synonyme: GRIK3 antikoerper, eaa5 antikoerper, glr7 antikoerper, glur7 antikoerper, 9630027E11 antikoerper, GluK3 antikoerper, GluR7-3 antikoerper, Glur-7 antikoerper, Glur7 antikoerper, GluR7 antikoerper, gluR-7 antikoerper, EAA5 antikoerper, GLR7 antikoerper, GLUR7 antikoerper, GluR7a antikoerper, glutamate ionotropic receptor kainate type subunit 3 antikoerper, glutamate receptor, ionotropic, kainate 3 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 3 antikoerper, GRIK3 antikoerper, grik3.L antikoerper, Grik3 antikoerper

Hintergrund:

Synonyms: EAA5, Excitatory amino acid receptor 5, GLR 7, GLR7, GLU R7, GLUR 7, GluR 7a, GluR-7, GLUR7, GluR7a, Glutamate receptor 7, Glutamate receptor, Glutamate receptor ionotropic kainate 3, GRIK 3, GRIK3, GRIK3_HUMAN, ionotropic kainate 3.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Pathways: Synaptic Membrane