NETO2 Antikörper (AA 151-250) (Alexa Fluor 350)

Produktnummer ABIN1393965

Produktdetails anti-NETO2 Antikörper (Alexa Fluor 350)

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Bindungsspezifität: AA 151-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NETO2 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NETO2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NETO2

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Andere Bezeichnung: NETO2 (NETO2 Produkte)

Synonyme: MGC145990 antikoerper, BTCL2 antikoerper, NEOT2 antikoerper, 5530601C23Rik antikoerper, AI854825 antikoerper, neuropilin and tolloid like 2 antikoerper, neuropilin (NRP) and tolloid (TLL)-like 2 antikoerper, NETO2 antikoerper, neto2 antikoerper, Neto2 antikoerper

Hintergrund:

Synonyms: Brain specic transmembrane protein, Brain specic transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2, Brain-specic transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, FLJ10430, FLJ14724, FLJ90456, NEOT2, NETO 2, Neto2, NETO2_HUMAN, Neuropilin NRP and tolloid TLL like 2, Neuropilin and tolloid like protein 2, Neuropilin and tolloid-like protein 2.

Background: NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.