DACT3 Antikörper (AA 575-629) (Alexa Fluor 555)

Produktnummer ABIN1393619

Produktdetails anti-DACT3 Antikörper (Alexa Fluor 555)

Target: DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))

Bindungsspezifität: AA 575-629

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DACT3 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DACT3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DACT3

Target: DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))

Andere Bezeichnung: DACT3 (DACT3 Produkte)

Synonyme: EG666671 antikoerper, naa-3 antikoerper, DAPPER3 antikoerper, RRR1 antikoerper, RGD1563892 antikoerper, dishevelled binding antagonist of beta catenin 3 antikoerper, dishevelled-binding antagonist of beta-catenin 3 antikoerper, DACT3 antikoerper, Dact3 antikoerper

Hintergrund:

Synonyms: Antagonist of beta-catenin Dapper homolog 3, Arginine rich region 1, Arginine rich region 1 protein, Arginine-rich region 1 protein, Dact3 antibody, DACT3_HUMAN, Dapper antagonist of beta catenin 3, Dapper antagonist of beta catenin homolog 3 Xenopus laevis, Dapper homolog 3, Dapper3, Dpr3 antibodyRRR1, RRR1, Thymus expressed gene 3 like.

Background: Dapper3 is a 629 amino acid protein and mammalian homolog of the Xenopus laevis protein dapper. As a member of the dapper family, Dapper3 plays a role in postnatal brain development and contains a C-terminal PDZ-binding motif that facilitates interaction with the PDZ domains of DSH (Dishevelled) family proteins. As the predominant dapper family member found in adult brain, Dapper 3 localizes to hippocampus, Purkinje cell layer and every layer of the dorsal forebrain and cerebral cortex and is also found in the developing murine central nervous system. Dapper3 is also expressed in uterus, ventral somites, branchial arch mesenchyme, aortic sac, aortic arches, limb bud mesenchyme and craniofacical mesenchyme. Mapping to human chromosome 19q13.32, Dapper3 has been identified as a negative regulator of Wnt/beta-catenin signaling in colorectal cancer.