CSDC2 Antikörper (AA 21-120) (Alexa Fluor 647)

Produktnummer ABIN1393536

Produktdetails anti-CSDC2 Antikörper (Alexa Fluor 647)

Target: CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSDC2 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIPPIN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CSDC2

Target: CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))

Andere Bezeichnung: CSDC2/PIPPIN (CSDC2 Produkte)

Synonyme: pippin antikoerper, csdc2 antikoerper, zgc:91826 antikoerper, PIPPIN antikoerper, dJ347H13.2 antikoerper, AI415250 antikoerper, AI481750 antikoerper, Pippin antikoerper, cold shock domain containing C2, RNA binding antikoerper, cold shock domain containing C2 antikoerper, cold shock domain containing C2, RNA binding a antikoerper, cold shock domain containing C2 L homeolog antikoerper, CSDC2 antikoerper, csdc2 antikoerper, csdc2a antikoerper, csdc2.L antikoerper, Csdc2 antikoerper

Hintergrund:

Synonyms: Cold shock domain containing C2 RNA binding, Cold shock domain containing protein C2, Cold shock domain-containing protein C2, CSDC 2, Csdc2, CSDC2_HUMAN, dJ347H13.2, PIPPIN, RNA binding protein PIPPin, RNA-binding protein PIPPin.

Background: PIPPIN is a Y-box protein (also called cold-shock (CSD) domain-containing protein) and belongs to a family of highly conserved RNA-binding transcriptional regulators. Predominantly expressed in brain cells and localizing to the nucleus and the cytoplasm, PIPPIN contains two RNA-binding motifs, namely PIP1 and PIP2, and one CSD domain. PIPPIN functions as a nucleic acid binding regulatory factor and is believed to participate in brain maturation. More specifically, PIPPIN binds to the 3?-UTR ends of the mRNAs encoding Histone H1 and Histone H3.3. This interaction requires all of the PIPPIN domains to work in concert as one functional protein. In addition, PIPPIN can be sumoylated in a thyroid hormone (T3)-dependent manner. This suggests that PIPPIN modification in response to extracellular stimuli may modulate the regulation of protein synthesis.