APPBP2 Antikörper (AA 201-300) (Alexa Fluor 488)

Produktnummer ABIN1392460

Produktdetails anti-APPBP2 Antikörper (Alexa Fluor 488)

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APPBP2 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APPBP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APPBP2

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Andere Bezeichnung: APPBP2 (APPBP2 Produkte)

Synonyme: HS.84084 antikoerper, PAT1 antikoerper, 1300003O07Rik antikoerper, AI465480 antikoerper, zgc:76971 antikoerper, wu:fb78e11 antikoerper, wu:fc25c09 antikoerper, APPBP2 antikoerper, DKFZp459F0530 antikoerper, amyloid beta precursor protein binding protein 2 antikoerper, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 antikoerper, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 S homeolog antikoerper, APPBP2 antikoerper, Appbp2 antikoerper, appbp2 antikoerper, appbp2.S antikoerper

Hintergrund:

Synonyms: amyloid beta precursor protein cytoplasmic tail binding protein 2, Amyloid beta precursor protein-binding protein 2, Amyloid protein binding protein 2, Amyloid protein-binding protein 2, APBP2_HUMAN, APP BP2, APP-BP2, Appbp2, PAT1, Ara67 Protein interacting with APP tail 1.

Background: APPBP2 is a hydrophilic, microtubule binding protein that functions in the trafficking of Beta-Amyloid precursor protein. It is expressed in a variety of cell types and localizes to the cytoplasm. APPBP2 shares homology with kinesin light chain. It consists of a coiled-coil domain, PKC phosphorylation sites, four imperfect C-terminal tandem repeats, eight tetratricopeptide repeats and N- and C-terminal globular structures. APPBP2 recognizes and binds to the basolateral sorting sequence (BaSS) present in the cytoplasmic domain of the Beta-Amyloid precursor protein. In addition, APPBP2 interacts with the androgen receptor and suppresses androgen signaling.

Gen-ID: 10513

UniProt: Q92624