TAS2R7 Antikörper (AA 121-220) (Alexa Fluor 350)

Produktnummer ABIN1392321

Produktdetails anti-TAS2R7 Antikörper (Alexa Fluor 350)

Target: TAS2R7 (Taste Receptor, Type 2, Member 7 (TAS2R7))

Bindungsspezifität: AA 121-220

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAS2R7 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAS2R7/T2R7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TAS2R7

Target: TAS2R7 (Taste Receptor, Type 2, Member 7 (TAS2R7))

Andere Bezeichnung: TAS2R7/T2R7 (TAS2R7 Produkte)

Synonyme: T2R7 antikoerper, TRB4 antikoerper, t2r1 antikoerper, t2r7 antikoerper, trb4 antikoerper, Patr-T2R7 antikoerper, taste 2 receptor member 7 antikoerper, taste receptor, type 2, member 7 antikoerper, TAS2R7 antikoerper, tas2r7 antikoerper

Hintergrund:

Synonyms: STC7 4, T2R30, T2R6, T2R7, TA2R7_HUMAN, Tas2r130, Tas2r6, TAS2R7, Taste receptor family B member 4, Taste receptor type 2 member 7, TRB4.

Background: The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Single taste receptor cells express a variety of T2Rs, suggesting that each cell is capable of recognizing multiple tastants. T2R6 (also designatedT2R30, mt2r42, STC 7-4 or taste receptor, type 2, member 130) is an integral membrane receptor protein in mice that may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate Alpha-gustducin, mediate PLC-Beta-2 activation and lead to the gating of TRPM5. T2R6 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. The human homolog of T2R6, designated T2R7 (TAS2R7, TRB4 or taste receptor, type 2, member 7) is a G protein-coupled receptor expressed in taste receptor cells of the tongue and palate epithelia.