SLIT1 Antikörper (AA 455-500) (Alexa Fluor 488)

Produktnummer ABIN1391554

Produktdetails anti-SLIT1 Antikörper (Alexa Fluor 488)

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Bindungsspezifität: AA 455-500

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLIT1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Slit1/MEGF4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLIT1

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Andere Bezeichnung: Slit1/MEGF4 (SLIT1 Produkte)

Synonyme: Slil1 antikoerper, mKIAA0813 antikoerper, MEGF4 antikoerper, SLIL1 antikoerper, SLIT-1 antikoerper, SLIT3 antikoerper, megf4 antikoerper, slil1 antikoerper, slit-1 antikoerper, SLIT1 antikoerper, slit3 antikoerper, slit homolog 1 (Drosophila) antikoerper, slit guidance ligand 1 antikoerper, slit guidance ligand 1 S homeolog antikoerper, slit homolog 1 protein antikoerper, slit homolog 1b (Drosophila) antikoerper, slit homolog 1a (Drosophila) antikoerper, Slit1 antikoerper, SLIT1 antikoerper, slit1.S antikoerper, slit1 antikoerper, LOC100459557 antikoerper, slit1b antikoerper, slit1a antikoerper

Hintergrund:

Synonyms: MEGF 4, MEGF4, Multiple EGF like domains protein 4, Multiple epidermal growth factor like domains 4, Multiple epidermal growth factor like domains protein 4, SLIL 1, SLIL1, Slit 1, SLIT 3, Slit homolog 1, Slit homolog 1 protein, Slit-1, Slit1, SLIT3, KIAA0813, SLIT1_HUMAN.

Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo) (1, 2). Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs (3,4). Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation (5). Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs (6,7).

Pathways: Regulation of Cell Size