Sauvagine (AA 1-40) Antikörper (Alexa Fluor 555)

Produktnummer ABIN1391195

Produktdetails

Target: Sauvagine

Bindungsspezifität: AA 1-40

Reaktivität: Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Xenopus laevis

Kreuzreaktivität (Details): Xenopus laevis

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from frog Sauvagine (C-QGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Sauvagine

Hintergrund:

Synonyms: Sauvagin, Sauvagine, SVG, SAUV_PHYSA.

Background: Sauvagine is a 40-residue peptide isolated and characterized from frog skin. It shares significant structural homology with and elicits similar biological responses as corticotropin-releasing factor (CRF). It has high affinity for both the CRF1 and CRF2 receptors (and low affinity for the CRF binding protein), suggesting its potential as a pharmacological tool for the study of these receptor sub-types. Due to the binding to CRF2 receptors and their role in the release of ACTH and beta-endorphin during stress, possible areas of research with this ligand include anxiety, depression and obesity.