TANC1 Antikörper (AA 31-130) (Biotin)
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- Target Alle TANC1 Antikörper anzeigen
- TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
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Bindungsspezifität
- AA 31-130
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TANC1 Antikörper ist konjugiert mit Biotin
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Applikation
- Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TANC1
- Isotyp
- IgG
- Top Product
- Discover our top product TANC1 Primärantikörper
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- Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
- Andere Bezeichnung
- TANC1 (TANC1 Produkte)
- Synonyme
- ROLSB antikoerper, TANC antikoerper, 1200003E16Rik antikoerper, Tanc antikoerper, mKIAA1728 antikoerper, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 antikoerper, TANC1 antikoerper, Tanc1 antikoerper
- Hintergrund
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Synonyms: ROLSB, Protein TANC1, Rolling pebbles homolog B, TANC, Tanc1, TANC1_HUMAN, Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1, Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1, TPR domain ankyrin repeat and coiled coil containing.
Background: TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8 % of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.
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