FAM84A Antikörper (AA 151-250) (Biotin)

Produktnummer ABIN1388749

Produktdetails anti-FAM84A Antikörper (Biotin)

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Bindungsspezifität: AA 151-250

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM84A Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Chicken,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NSE1/FAM84A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FAM84A

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Andere Bezeichnung: Nse1/Fam84a (FAM84A Produkte)

Synonyme: 2310003N02Rik antikoerper, 4731402F03Rik antikoerper, AW125753 antikoerper, Nse1 antikoerper, NSE1 antikoerper, PP11517 antikoerper, RGD1305779 antikoerper, zgc:63724 antikoerper, family with sequence similarity 84, member A antikoerper, family with sequence similarity 84 member A antikoerper, Fam84a antikoerper, FAM84A antikoerper, fam84a antikoerper

Hintergrund:

Synonyms: FAM 84A, Family with sequence similarity 84 member A, family with sequence similarity 84, member A, FLJ35392, Neurologic sensory protein 1, Neurological/sensory 1, NSE 1, NSE1, PP11517, Protein FAM84A, Protein NSE1.

Background: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44 % amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

Gen-ID: 3859