FAM62B Antikörper (AA 801-921) (Alexa Fluor 488)

Produktnummer ABIN1388704

Produktdetails anti-FAM62B Antikörper (Alexa Fluor 488)

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Bindungsspezifität: AA 801-921

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM62B Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ESYT2/FAM62B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FAM62B

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Andere Bezeichnung: ESYT2/FAM62B (ESYT2 Produkte)

Synonyme: CHR2SYT antikoerper, E-Syt2 antikoerper, FAM62B antikoerper, 2410017M09Rik antikoerper, 4921504I16Rik antikoerper, D12Ertd551e antikoerper, Fam62b antikoerper, extended synaptotagmin 2 antikoerper, extended synaptotagmin-like protein 2 antikoerper, ESYT2 antikoerper, Esyt2 antikoerper

Hintergrund:

Synonyms: Chr2 synaptotagmin, CHR2SYT, E Syt2, ESYT 2, ESYT2, Extended synaptotagmin 2, Extended synaptotagmin like protein 2, FAM 62B antibody Family with sequence similarity 62 C2 domain containing member B, Family with sequence similarity 62 member B, KIAA1228, Protein FAM62B, ESYT2_HUMAN.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM62A gene product has been provisionally designated FAM62A pending further characterization.