SYNM Antikörper (AA 501-650)

Produktnummer ABIN1387897

Produktdetails anti-SYNM Antikörper

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Bindungsspezifität: AA 501-650

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNM Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Desmuslin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SYNM Antikörper (ABIN1387897)

Bengoechea, Pittman, Tuck, True, Weihl: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." in: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).

Details zu SYNM

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Andere Bezeichnung: Desmuslin (SYNM Produkte)

Synonyme: DMN antikoerper, dmn antikoerper, si:dkey-25f3.3 antikoerper, SYN antikoerper, 4930412K21Rik antikoerper, AI852401 antikoerper, Dmn antikoerper, E130104F11 antikoerper, Syn antikoerper, Synemin antikoerper, synemin antikoerper, synemin, intermediate filament protein antikoerper, SYNM antikoerper, synm antikoerper, Synm antikoerper

Hintergrund:

Synonyms: DMN, SYN, Synemin, Desmuslin, SYNM, KIAA0353

Background: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

Gen-ID: 23336

UniProt: O15061