SEMA3E Antikörper (AA 401-450)

Produktnummer ABIN1387869

Produktdetails anti-SEMA3E Antikörper

Target: SEMA3E (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3E (SEMA3E))

Bindungsspezifität: AA 401-450

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEMA3E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SEMA3E

Target: SEMA3E (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3E (SEMA3E))

Andere Bezeichnung: SEMA3E/Semaphorin 3E (SEMA3E Produkte)

Synonyme: M-SEMAH antikoerper, M-SemaK antikoerper, SEMAH antikoerper, coll-5 antikoerper, 6430702L12 antikoerper, AA408817 antikoerper, Semah antikoerper, mKIAA0331 antikoerper, semaphorin 3E antikoerper, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E antikoerper, SEMA3E antikoerper, Sema3e antikoerper

Hintergrund:

Synonyms: Coll 5, Coll5, KIAA0331, M sema H, M SEMAH, M SemaK, Msema H, MSEMAH, MSemaK, SEM3E_HUMAN, Sema domain immunoglobulin domain Ig, Sema domain immunoglobulin domain Ig short basic domain secreted 3E, Sema domain, immunoglobulin domain Ig, short basic domain, secreted, semaphorin 3E, SEMA3E, SEMAH, Semaphorin 3E, Semaphorin-3E, Semaphorin3E, Short basic domain secreted semaphorin 3E, SEM3E_HUMAN.

Background: Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular semaphorin? domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.