SLC9A3 Antikörper (pSer552)

Produktnummer ABIN1387624

Produktdetails anti-SLC9A3 Antikörper

Target: SLC9A3 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3))

Bindungsspezifität: pSer552

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC9A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NHE-3 around the phosphorylation site of Ser552 [RG(p-S)LA](human Ser555)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SLC9A3

Target: SLC9A3 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3))

Andere Bezeichnung: NHE3 (SLC9A3 Produkte)

Synonyme: SLC9A3 antikoerper, 9030624O13Rik antikoerper, AI930210 antikoerper, NHE-3 antikoerper, NHE3 antikoerper, Nhe3 antikoerper, solute carrier family 9 member A3 antikoerper, sodium/hydrogen exchanger 3 antikoerper, Sodium/hydrogen exchanger 3 antikoerper, putative sodium/hydrogen exchanger 3 (nhe3) antikoerper, solute carrier family 9 (sodium/hydrogen exchanger), member 3 antikoerper, SLC9A3 antikoerper, LOC5570922 antikoerper, GL50803_102647 antikoerper, Smp_045680 antikoerper, Slc9a3 antikoerper

Hintergrund:

Synonyms: p-NHE-3, Sodium / Hydrogen Exchanger 3 phospho S552, Na+/H+ exchanger 3, NHE 3, NHE-3, NHE3, SL9A3_HUMAN, SLC9A 3, Slc9a3, Sodium/hydrogen exchanger 3, Sodium/hydrogen exchanger, apical epithelial, Solute carrier family 9 sodium/hydrogen exchanger, isoform 3, Solute carrier family 9 sodium/hydrogen exchanger, member 3, Solute carrier family 9 member 3, MGC126718, MGC126720.

Background: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.

Pathways: Proton Transport