TRPM7 Antikörper (AA 800-850)

Produktnummer ABIN1387614

Produktdetails anti-TRPM7 Antikörper

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Bindungsspezifität: AA 800-850

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRPM7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TRPM7

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Andere Bezeichnung: TRPM7 (TRPM7 Produkte)

Synonyme: cb495 antikoerper, TRPM7 antikoerper, chak antikoerper, chak1 antikoerper, ltrpc7 antikoerper, trp-plik antikoerper, ALSPDC antikoerper, CHAK antikoerper, CHAK1 antikoerper, LTRPC7 antikoerper, TRP-PLIK antikoerper, 2310022G15Rik antikoerper, 4833414K03Rik antikoerper, 5033407O22Rik antikoerper, LTrpC-7 antikoerper, Ltpr7 antikoerper, Ltrpc7 antikoerper, TRPPLIK antikoerper, Chak antikoerper, Trp-plik antikoerper, transient receptor potential cation channel subfamily M member 7 antikoerper, transient receptor potential cation channel, subfamily M, member 7 antikoerper, TRPM7 antikoerper, trpm7 antikoerper, Trpm7 antikoerper

Hintergrund:

Synonyms: CHAK, CHAK1, ALSPDC, LTRPC7, LTrpC-7, TRP-PLIK, Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, TRPM7

Background: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

Gen-ID: 54822

UniProt: Q96QT4