KCNJ10 Antikörper (AA 81-180)

Produktnummer ABIN1387583

Produktdetails anti-KCNJ10 Antikörper

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Bindungsspezifität: AA 81-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ10 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kir4.1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Andere Bezeichnung: Kir4.1 (KCNJ10 Produkte)

Synonyme: kir1.2 antikoerper, kir4.1 antikoerper, birk-10 antikoerper, MGC145926 antikoerper, BIR10 antikoerper, BIRK-1 antikoerper, Kir1.2 antikoerper, Kir4.1 antikoerper, BIRK-10 antikoerper, KCNJ13-PEN antikoerper, KIR1.2 antikoerper, KIR4.1 antikoerper, SESAME antikoerper, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog antikoerper, potassium voltage-gated channel subfamily J member 10 antikoerper, potassium channel, inwardly rectifying subfamily J, member 10 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 10 antikoerper, kcnj10.L antikoerper, KCNJ10 antikoerper, kcnj10 antikoerper, Kcnj10 antikoerper

Hintergrund:

Synonyms: ATP dependent inwardly rectying potassium channel Kir4.1, ATP sensitive inward rectier potassium channel 10, ATP-dependent inwardly rectying potassium channel Kir4.1, ATP-sensitive inward rectier potassium channel 10, BIRK10, Glial ATP dependent inwardly rectying potassium channel KIR4.1, Inward rectier K+ channel Kir1.2, Inward rectier K+ channel KIR1.2, Inwardly rectying potassium channel Kir1.2, inwardly rectying subfamily J member 10, KCNJ 10, Kcnj10, KCNJ13 PEN, KIR1.2, KIR4.1, Potassium channel, Potassium channel inwardly rectying subfamily J member 10, Potassium inwardly rectying channel subfamily J member 10, SESAME, IRK10_HUMAN.

Background: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down?s syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.

Gen-ID: 3766

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity