NR6A1 Antikörper (AA 251-350)

Produktnummer ABIN1387521

Produktdetails anti-NR6A1 Antikörper

Target: NR6A1 (Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR6A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCNF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NR6A1

Target: NR6A1 (Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1))

Andere Bezeichnung: GCNF (NR6A1 Produkte)

Synonyme: GCNF antikoerper, GCNF1 antikoerper, NR61 antikoerper, RTR antikoerper, hGCNF antikoerper, hRTR antikoerper, 1700113M01Rik antikoerper, Gcnf antikoerper, NCNF antikoerper, gcnf antikoerper, xEmGCNF antikoerper, gcnf1 antikoerper, nr61 antikoerper, rtr antikoerper, xGCNF antikoerper, NR6A1 antikoerper, GCNF-B antikoerper, si:ch211-167p9.1 antikoerper, zC167P9.1 antikoerper, zgc:114189 antikoerper, nr6a1 antikoerper, zfGCNF antikoerper, nuclear receptor subfamily 6 group A member 1 antikoerper, nuclear receptor subfamily 6, group A, member 1 antikoerper, nuclear receptor subfamily 6 group A member 1 S homeolog antikoerper, nuclear receptor subfamily 6, group A, member 1b antikoerper, nuclear receptor subfamily 6, group A, member 1a antikoerper, NR6A1 antikoerper, Nr6a1 antikoerper, nr6a1.S antikoerper, nr6a1 antikoerper, nr6a1b antikoerper, nr6a1a antikoerper

Hintergrund:

Synonyms: GCNF 1, GCNF, GCNF1, Germ cell nuclear factor, hGCNF, hRTR, NR 61, NR61, NR6A1, NR6A1_HUMAN, Nuclear receptor subfamily 6 group A member 1, Orphan nuclear receptor NR6A1, Retinoic acid receptor related testis associated receptor, Retinoid receptor related testis specic receptor, Retinoid receptor-related testis-specic receptor, RTR.

Background: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis, northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway