ESYT1 Antikörper (AA 651-750)

Produktnummer ABIN1387363

Produktdetails anti-ESYT1 Antikörper

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Bindungsspezifität: AA 651-750

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Rabbit,Monkey

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ESYT1/FAM62A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ESYT1

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Andere Bezeichnung: ESYT1/FAM62A (ESYT1 Produkte)

Synonyme: FAM62A antikoerper, fam62a antikoerper, si:ch211-239j9.4 antikoerper, DKFZp459I1628 antikoerper, MBC2 antikoerper, Fam62a antikoerper, Mbc2 antikoerper, vp115 antikoerper, extended synaptotagmin 1 antikoerper, extended synaptotagmin-like protein 1b antikoerper, extended synaptotagmin-like protein 1 antikoerper, ESYT1 antikoerper, esyt1b antikoerper, Esyt1 antikoerper

Hintergrund:

Synonyms: Extended synaptotagmin 1, KIAA0747, E Syt1, E-Syt1, Esyt1, ESYT1_HUMAN, Extended synaptotagmin like protein 1, Extended synaptotagmin-1, Family with sequence similarity 62 C2 domain containing member A, Family with sequence similarity 62 member A, MBC2, Membrane bound C2 domain containing protein, Membrane-bound C2 domain-containing protein, Protein FAM62A.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM62A gene product has been provisionally designated FAM62A pending further characterization.