MARCH7 Antikörper (AA 65-115)

Produktnummer ABIN1387036

Produktdetails anti-MARCH7 Antikörper

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Bindungsspezifität: AA 65-115

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IP(1-2 μg)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MARCH7 Antikörper (ABIN1387036)

Zhang, Wang, Tian, Li: "Expression of USP7 and MARCH7 Is Correlated with Poor Prognosis in Epithelial Ovarian Cancer." in: The Tohoku journal of experimental medicine, Vol. 239, Issue 3, pp. 165-75, (2016) (PubMed).

Hu, Meng, Yu, Hu, Mao: "Ubiquitin E3 ligase MARCH7 promotes ovarian tumor growth." in: Oncotarget, Vol. 6, Issue 14, pp. 12174-87, (2015) (PubMed).

Details zu MARCH7

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Andere Bezeichnung: MARCH7 (MARCH7 Produkte)

Synonyme: AXO antikoerper, AXOT antikoerper, MARCH-VII antikoerper, RNF177 antikoerper, Mar-07 antikoerper, MARCH7 antikoerper, axot antikoerper, axotrophin antikoerper, march-vii antikoerper, rnf177 antikoerper, DKFZp468P155 antikoerper, Axo antikoerper, Axot antikoerper, Gtrgeo17 antikoerper, membrane associated ring-CH-type finger 7 antikoerper, membrane associated ring-CH-type finger 7 S homeolog antikoerper, membrane-associated ring finger (C3HC4) 7 antikoerper, MARCH7 antikoerper, march7.S antikoerper, march7 antikoerper, March7 antikoerper

Hintergrund:

Synonyms: AXO, AXOT, Axotrophin, E3 ubiquitin-protein ligase MARCH7, MARCH VII, MARCH-VII, March7, MARH7_HUMAN, Membrane associated RING CH protein VII, Membrane associated ring finger C3HC4 7 E3 ubiquitin protein ligase, membrane associated ring finger C3HC4 7, Membrane associated RING finger protein 7, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, RING finger protein 177, RNF177.

Background: Axotrophin is a stem cell gene that encodes a protein which is involved in T lymphocyte regulation (especially in regulating the proliferation) and leukemia inhibitory factor (LIF) release. LIF is a neuropoietic cytokine that is important for stem cell regulation and thymocyte stimulation. Both Axotrophin and LIF are linked to transplantation intolerance. Axotrophin is also involved in corpus callosum differentiation and may play a role in glial cell line-derived neurotrophic factor (GDNF)-dependent sensory neuron survival in the substantia gelatinosa of the adult spinal cord. Axotrophin is primarily expressed in the hippocampus, cortex, purkinje and granule cells of the cerebellum.

Gen-ID: 64844

UniProt: Q9H992