RCBTB1 Antikörper

Produktnummer ABIN1386881

Produktdetails anti-RCBTB1 Antikörper

Target: RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCBTB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RCBTB1/CLLD7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RCBTB1

Target: RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))

Andere Bezeichnung: RCBTB1 (RCBTB1 Produkte)

Synonyme: fj43a07 antikoerper, zgc:56037 antikoerper, wu:fj43a07 antikoerper, MGC81035 antikoerper, rcbtb1 antikoerper, CLLD7 antikoerper, CLLL7 antikoerper, GLP antikoerper, RP11-185C18.1 antikoerper, 5430409I18Rik antikoerper, AW111883 antikoerper, RCC1 and BTB domain containing protein 1 antikoerper, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antikoerper, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 S homeolog antikoerper, RCC1 and BTB domain-containing protein 1 antikoerper, Rcbtb1 antikoerper, RCBTB1 antikoerper, rcbtb1 antikoerper, rcbtb1.S antikoerper, LOC100470400 antikoerper

Hintergrund:

Synonyms: Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, CLLD7, CLLL7 protein, Guanine nucleotide exchange factor, broad-complex, tramtrack and bric a brac, Hypothetical protein FLJ39335, RCBT1_HUMAN, Rcbtb1, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1.

Background: The BTB domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. RCBTB1 (regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1), also known as GLP, CLLD7, CLLL7 or E4.5, is a 531 amino acid protein that localizes to the nucleus and contains two BTB (POZ) domains and six RCC1 repeats. Expressed ubiquitously, RCBTB1 is thought to be involved in cell cycle regulation, specifically via chromatin remodeling. The gene encoding RCBTB1 maps to a region on human chromosome 13 that is frequently deleted in B-cell chronic lymphocytic leukemia, suggesting a possible role for RCBTB1 in tumor suppression.

Gen-ID: 55213