GNAL Antikörper (AA 21-130)

Produktnummer ABIN1386650

Produktdetails anti-GNAL Antikörper

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Bindungsspezifität: AA 21-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNAL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNAL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GNAL

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Andere Bezeichnung: GNAL (GNAL Produkte)

Synonyme: DYT25 antikoerper, zgc:103521 antikoerper, 2610011C15Rik antikoerper, 9630020G10Rik antikoerper, AI843190 antikoerper, Galphaolf antikoerper, Gna10 antikoerper, Golf antikoerper, Olf antikoerper, RGD1305940 antikoerper, G protein subunit alpha L antikoerper, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type antikoerper, guanine nucleotide binding protein, alpha stimulating, olfactory type antikoerper, GNAL antikoerper, gnal antikoerper, Gnal antikoerper

Hintergrund:

Synonyms: Adenylate cyclase stimulating G alpha protein, olfactory type, Adenylate cyclase stimulating G alpha protein, olfactory type, Adenylate cyclase-stimulating G alpha protein, Gnal, GNAL_HUMAN, Guanine nucleotide binding protein G protein, alpha activating activity polypeptide, olfactory type, Guanine nucleotide binding protein G protein, alpha stimulating activity polypeptide, olfactory type, Guanine nucleotide binding protein Golf subunit alpha, Guanine nucleotide-binding protein Golf subunit alpha, olfactory type.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. More recent evidence, however, has established an important regulatory role for the beta gamma subunits (6-8). The Gs subfamily of G alpha subunits includes two closely related proteins, Ga s and Ga olf, which respectively stimulate adenylate cyclase and mediate response to olfactory stimuli (9).