MPP5 Antikörper (AA 201-300)
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- Target Alle MPP5 Antikörper anzeigen
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MPP5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MPP5/PALS1
- Isotyp
- IgG
- Top Product
- Discover our top product MPP5 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
- Andere Bezeichnung
- MPP5/PALS1 (MPP5 Produkte)
- Synonyme
- PALS1 antikoerper, 3830420B02Rik antikoerper, AI255216 antikoerper, AI644496 antikoerper, Pals1 antikoerper, mpp5 antikoerper, nok antikoerper, MAGUK p55 subfamily member 5 antikoerper, membrane palmitoylated protein 5 antikoerper, membrane protein, palmitoylated 5 L homeolog antikoerper, membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) antikoerper, membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) antikoerper, Tsp_03061 antikoerper, MPP5 antikoerper, mpp5.L antikoerper, Mpp5 antikoerper, mpp5a antikoerper
- Hintergrund
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Synonyms: FLJ12615, MAGUK p55 subfamily member 5, Membrane protein palmitoylated 5, MPP 5, MPP5, MPP5_HUMAN, PALS 1, PALS1, Protein associated with Lin-7, Stardust Drosophila, Stardust.
Background: Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
- Pathways
- Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization
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