Homeobox C5 Antikörper (AA 151-222)

Produktnummer ABIN1385993

Produktdetails anti-Homeobox C5 Antikörper

Target: Homeobox C5 (HOXC5)

Bindungsspezifität: AA 151-222

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Homeobox C5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXC5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Homeobox C5

Target: Homeobox C5 (HOXC5)

Andere Bezeichnung: HOXC5 (HOXC5 Produkte)

Synonyme: ZF-25 antikoerper, hox-3.4 antikoerper, hoxc5 antikoerper, z-142 antikoerper, XlHbox5 antikoerper, hoxc5-A antikoerper, CP11 antikoerper, HOX3 antikoerper, HOX3D antikoerper, AI181837 antikoerper, Hox-3.4 antikoerper, Hox-6.2 antikoerper, homeobox C5 antikoerper, homeo box C5 antikoerper, homeobox C5a antikoerper, homeobox C5 L homeolog antikoerper, translation initiation factor IF-2 antikoerper, HOXC5 antikoerper, Hoxc5 antikoerper, hoxc5a antikoerper, hoxc5.L antikoerper, LOC607625 antikoerper

Hintergrund:

Synonyms: CP11, homeo box C5, homeobox C5, Homeobox protein CP11, homeobox protein Hox C5, Homeobox protein Hox-3D, Homeobox protein Hox-C5, Hox 3D, HOX3, HOX3D, HOXC5, HXC5_HUMAN, OTTHUMP00000217386.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.