CELSR2 Antikörper (AA 201-300)

Produktnummer ABIN1385874

Produktdetails anti-CELSR2 Antikörper

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELSR2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CELSR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CELSR2

Target: CELSR2 (Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2))

Andere Bezeichnung: CELSR2 (CELSR2 Produkte)

Synonyme: CDHF10 antikoerper, EGFL2 antikoerper, Flamingo1 antikoerper, MEGF3 antikoerper, Megf3 antikoerper, flamingo antikoerper, mKIAA0279 antikoerper, mfmi1 antikoerper, cadherin EGF LAG seven-pass G-type receptor 2 antikoerper, cadherin, EGF LAG seven-pass G-type receptor 2 antikoerper, CELSR2 antikoerper, Celsr2 antikoerper

Hintergrund:

Synonyms: Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog, Cadherin EGF LAG seven-pass G-type receptor 2, Cadherin family member 10, CDHF10, CELR2_HUMAN, Celsr2, EGF like domain multiple 2, EGF-like protein 2, EGFL2, epidermal growth factor like 2, Epidermal growth factor-like protein 2, Flamingo homolog 3, Flamingo1, KIAA0279, MEGF3, Multiple EGF-like domains protein 3, Multiple epidermal growth factor-like domains protein 3.

Background: Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.